On-again, off-again alt-rockers Jane's Addiction are locked in to play CBS' 'Late Show With David Letterman' tonight (Oct. 24). Frontman Perry Farrell, guitarist Dave Navarro and drummer Stephen Perkins, along with Chris Chaney on bass, will likely perform a song off their recently released 'The Great Escape Artist,' the group's first studio album since 2003.

Jane's Addiction have a long history of incredible success, personal struggles and frequent line-up changes (including Guns N' Roses bassist Duff McKagan and Flea from the Red Hot Chili Peppers). Luckily for fans however, the band has stuck together to successfully record 'The Great Escape Artist,' which dropped on Oct. 18. One of the new album's songs -- 'Underground' -- is currently available as a free download on the Lollapalooza website.

Jane's Addiction took a gutsy approach with recording 'The Great Escape Artist,' collaborating with innovative TV on the Radio guitarist Dave Sitek to give the album a unique twist of modern indie-rock sensibility. "I love the fact that we haven’t sat back on our heels and depended on our reputation," stated Farrell in an interview with the New York Post. "I couldn’t live with myself, I wouldn’t be happy if we just made another Jane’s record like the last record. It’s risky, but I like to live a risky and dangerous life. I wouldn’t do it any other way."

Tune in tonight at 11:35PM ET to see Jane's Addiction on CBS' 'Late Show With David Letterman.'

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